Endur-Amide SR 500mg
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Endur-Amide SR 500mg

ENDUR-AMIDE® Niacinamide is a sustained-release dietary supplement featuring niacinamide, the preferred form of niacin for healthy cell division, skin health and healthy aging benefits. The SmartMatrix ™ tablet releases this versatile nutrient slowly over 5 to 7 hours for optimal absorption.

  • Easy to swallow tablets 
  • NO salt, sugar, starch, artificial colors or flavorings, or preservatives
  • Gluten-free
  • Vegan/Vegetarian
  • Free of common allergens (milk, egg, fish, shellfish, tree nuts, peanuts, wheat and soy)
  • Sustained release (5-7 hours)
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Product Info Sheet: Download Here
Clinical-Strength Formulation
SmartMatrix™ Sustained-Release
U.S. Manufactured, cGMP Certified

ENDUR - AMIDE® Niacinamide features niacinamide, the preferred form of niacin for healthy cell division, skin health and healthy aging benefits. With SmartMatrix ™ delivery, each tablet releases niacinamide in a slow, steady manner over 5 to 7 hours for optimal absorption.

Niacinamide is a precursor for the body ’ s production of nicotinamide adenine dinucleoti de (NAD+), an essential pyridine nucleotide present in all living cells.

NAD+ acts as an important cofactor and substrate for a multitude of biological processes including energy production, DNA repair, gene expression, calcium - dependent secondary messeng er signaling, and immunoregulatory roles.

Directions: Take one (1) to three (3) tablets daily with food or drink, or as directed by your healthcare professional. Do not exceed recommended dose without consulting a physician.

Clean Formulas

No Preservatives

Gluten-free

Vegan Options

No Artificial Flavors

  • Helps offset the age - related decline in NAD+. As an NAD+ precursor, niacinamide helps offset the age - related decline in NAD+ production in cells and tissues. The age-related depletion of NAD+ in aging cells isattributed to the need for more NAD+ to meet the metabolic demands ofaging, the inability of aging cells to adequately synthesize enough NAD+to meet metabolic demands, or both (1).
  • Promotes a healthy inflammatory response. Oral niacinamide actssystemically to support the body’s natural anti-inflammatory response byhelping modulate the activity of inflammatory cytokines and reduceoxidative stress (2).
  • Supports healthy skin cells. Randomized controlled trials indicate oralniacinamide (500 mg, once or twice daily) support healthy skin cells inmiddle-aged and older adults (3,4). While the mechanism of action isunclear, the researchers suggest DNA repair and/or immune protection playa role (5).

Niacinamide & Healthy Aging

One extensive systematic review of preclinical and clinical researchindicates niacinamide effectively increases NAD+ levels. This action supportsoptimal mitochondrial function, cellular metabolism, DNA repair, and keycellular pathways needed for many key aspects of resilience during aging suchas hearing,vision, neurological activity, muscle function, and cardiometabolic, joint, liver, and skin cell health. By supporting theseessential processes, niacinamide promotes vitality and healthy aging (6).

NAD+ Production: Key Healthy Aging Benefits

  • Cardiometabolic Health
  • Healthy Vision
  • Healthy Hearing
  • Joint Health
  • Liver Health
  • Muscle Function
  • Neurological Function
  • Skin Health

Other Ingredients: Vegetable wax (rice bran and/or carnauba), stearic acid(vegetable), magnesium stearate (vegetable), and silica.

ENDUR-AMIDE® Niacinamideis manufactured in the United States (Oregon) in astate-of-the-art, FDA-registered facility that meets or exceeds current Good Manufacturing Practices (cGMP). Quality control tests are performed at everystage of the manufacturing process from rigorous raw material testing tofinished product testing.

Precautions

Consult your healthcare professional prior to use if you have or suspect amedical condition, are taking any medications, or are pregnant or nursing.

References

  • McReynolds MR, et al. Exp Gerontol. 2020;134:110888.
  • Marques C, et al. Antioxidants (Basel). 2024;13(4):425.
  • Surjana D, et al. J Invest Dermatol. 2012;132(5):1497-1500.
  • Chen AC, et al. N Engl J Med. 2015;373(17):1618-1626.
  • Braidy N, et al. Exp Gerontol. 2020;132:110831.

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within 30 days of purchase

Sustained Release

over 5–7 hours for lasting effect.