PepZin GI 75mg Chewable
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PepZin GI 75mg Chewable

PepZin GI® Zinc-Carnosine is a chewable dietary supplement featuring a clinically validated form of zinc that promotes stomach & digestive health*

  • Chewable tablets for use with or without food
  • NO salt, sugar, yeast, wheat gluten, or preservatives
  • Gluten-free
  • Vegan/Vegetarian
  • Free of common allergens (milk, egg, fish, shellfish, tree nuts, peanuts, wheat and soy)

PepZin GI® is a registered trademark of Hamari Chemicals LTD.

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Product Info Sheet: Download Here
Clinical-Strength Formulation
SmartMatrix™ Sustained-Release
U.S. Manufactured, cGMP Certified

PepZinGI® Zinc-Carnosinefeatures a clinically validated zinc-carnosinechelate that helps fortify the protective mucous membrane lining the stomachand intestines.

PepZinGI® is a unique chelate in which zinc is bound to the dipeptide L-carnosine, forming a stable complex. It has been used for decades in Japan topromote the health and integrity of the stomach mucosal lining and supportgastric health. Its unique form allows it to remain stable in stomach acidand adhere to mucosa, where it gradually releases zincand L-carnosine. Thekey mechanisms of action include:1

--Helps stabilize cells membranes, supporting mucosal integrity
--Scavenges free radicals and supports antioxidant enzyme activity, loweringoxidative stress
--Helps modulate the body’s natural inflammatory response
--Helps stimulate protective proteins like heat shock proteins, aiding cellprotection

The gastric health effects of PepZinGI® are independent of acid reduction asit does not suppress gastric acid secretion or alter prostaglandin E2levels.L-carnosine is metabolized locally and does not enter the bloodstream, whilezinc is absorbed with minimal impact on overall zinc levels (1)

Directions: As a dietary supplement, take or chew one (1) tablet, twice dailywith or without meals, or as directed by your healthcare practitioner.

Clean Formulas

No Preservatives

Gluten-free

Vegan Options

No Artificial Flavors

PepZinGI® is clinically validated to support GI mucosal health

  • Supports Intestinal Mucosal Integrity. One double-blind, placebo-controlled, crossover study indicates that PepZinGI® helps support andstabilize the mucosal lining in the small intestine and is well tolerated(2). Dosage: 37.5 mg, twice daily.
  • Supports Stomach Mucosal Integrity. One multi-center, double-blind studyindicates that PepZinGI® helps support and stabilizethe mucosal lining inthe stomach and is well tolerated (3). Dosage: 75 mg, twice daily.
  • Promotes Digestive Comfort. One multi-center, double-blind, controlledstudy indicates that PepZinGI® supports digestive comfort, helps maintainthe integrity of the stomach mucosa, and is well tolerated (4). Dosage: 75mg, twice daily.

PepZinGI® Zinc-Carnosine is the only zinc L-carnosine that has undergone anFDA review for safety and human use, resulting in New Dietary Ingredient(NDI) status foradults and children over 12.
--Adults and children over 12: Maximum daily intake is 150 mg/day (providing34 mg elemental zinc).
--Elderly: Reduce maximum daily intake to less than 100 mgdue to reduced digestive function.
--Children under 12, pregnant and lactating women: Not recommended due tolack of safety data.
This added measure of regulatory oversight further supports PepZinGI® as atrusted option for your clinical practice.

Other Ingredients: Isomalt (vegetable), stearic acid (vegetable), magnesiumstearate (vegetable), modified cellulose (vegetable), and silica.

PepZin GI® Zinc L-Carnosineis manufactured in the United States (Oregon) ina state-of-the-art, FDA-registered facility that meets or exceeds currentGood Manufacturing Practices (cGMP). Quality control tests are performed atevery stage of the manufacturing process from rigorous raw material testingto finished product testing.

Precautions

Consult your healthcare professional prior to use if you have or suspect amedical condition, are taking any medications, or are pregnant or nursing.

References

  1. Efthymakis K, et al. Clinical Research in Hepatology and Gastroenterology. 2022;46(7):101954.
  2. Mahmood A, et al. Gut. 2007;56(2):168–175.
  3. Miyoshi A, et al. Japanese Pharmacology & Therapeutics. 1992;20(1):199–223
  4. Nakajima M, et al. Japanese Pharmacology & Therapeutics. 1997;25(4):325–366.

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Free Returns

within 30 days of purchase

Sustained Release

over 5–7 hours for lasting effect.